At Least 5 Dead, 5 Injured After Amazon Boeing 767 Crashes at Miami Airport

At least five people were killed and five others injured after an Amazon Prime Air cargo plane overran a runway at Miami International Airport on Sunday, Sept. 6, striking multiple vehicles and catching fire.

The crash involved Prime Air Flight 7598, a Boeing 767-300 operated by 21 Air. The aircraft had departed from Luis Muñoz Marín International Airport in San Juan, Puerto Rico, before the accident occurred shortly before 2 p.m. local time.

Miami-Dade County Mayor Daniella Levine Cava confirmed that five people had died and five others were injured. Three of those injured were in critical condition, while two others were taken to a local hospital.

Plane veered off runway and struck vehicles

According to the Federal Aviation Administration, Flight 7598 overran the airport’s diagonal runway while landing and came to rest near the northwest end of the airport. Miami-Dade Fire Rescue said the aircraft struck multiple vehicles after leaving the runway.

The crash quickly turned into a major emergency response. Witnesses captured footage showing the large cargo jet surrounded by flames, with thick black smoke rising above the airport area.

Emergency crews rushed to the scene as the aircraft burned. More than 60 Miami-Dade Fire Rescue units responded, with firefighters working to contain the fire and assess those affected by the crash.

The identities of those who died or were injured had not been publicly released.

Pilots among those hospitalized

The aircraft’s two pilots were reportedly among those injured and were taken to a nearby hospital along with the other wounded, according to local reports.

The crash created a complicated rescue operation, with emergency personnel responding both to the damaged aircraft and to vehicles that had been struck after the plane left the runway.

Although the scene showed extensive fire and smoke, images from the aftermath indicated that much of the aircraft remained recognizable despite the damage.

Authorities have not yet determined what caused the Boeing 767 to leave the runway. The FAA and National Transportation Safety Board are investigating the crash.

Miami airport operations disrupted

The accident immediately brought operations at one of the country’s busiest airports to a halt.

A ground stop was put in place, while all runways and taxiways were initially closed as emergency crews dealt with the wreckage. The airport remained heavily disrupted as authorities worked at the scene.

By Sunday evening, two of the airport’s four runways had reopened, while significant delays and cancellations continued.

The disruption came as travelers were moving through Miami International Airport, with officials warning passengers to expect delays and possible cancellations following the crash.

Amazon responds as investigation begins

Amazon confirmed that an aircraft operated on its behalf by 21 Air had experienced an incident while attempting to land.

The company said it was working closely with local authorities and officials to determine what happened and expressed sympathy for those affected.

“We’re heartbroken to learn that five people lost their lives in today’s incident at Miami International Airport,” an Amazon spokesperson said. “Our deepest sympathies go out to the families, loved ones, and all those affected by this devastating loss.”

Mayor Levine Cava also offered condolences to the victims’ families and praised the emergency crews who responded.

“I am grateful to our Miami-Dade Fire Rescue teams and all the first responders who rushed to the scene,” she said. “Our community stands together tonight with all those impacted as we continue to learn more.”

The cause of the crash remains under investigation.

Another major cargo-plane accident in recent years

Sunday’s disaster comes amid a series of serious incidents involving cargo aircraft near major U.S. airports.

In November 2025, a UPS cargo plane caught fire and crashed while taking off from Muhammad Ali International Airport in Louisville, Kentucky. The incident was captured on dashcam video from a nearby truck.

Then, in May, a truck traveling on the New Jersey Turnpike was struck by a plane that was landing too low near Newark International Airport.

Investigators will now work to establish exactly why Amazon Prime Air Flight 7598 overran the Miami runway and determine the circumstances that led to the deadly crash.